3-D Life Biomimetic Hydrogels -
Cell Environment Design at Your Fingertips

Cellendes is a life science company offering comprehensive solutions for controlled design of cell environments in 3-D cell culture. A toolbox of reagents provides flexibility in composing biomimetic hydrogels right at the users bench. Areas of application include basic research, drug development and biomedical engineering.

 

Brochure  

Learn more about the flexible design of 3-D Life Hydrogels

  • Control over cell spreading and migration
  • Independent variation of peptide densities and gel strength
  • Easy recovery of cells after culture
  • Guide to hydrogel compositions for your cell cultures

 

De novo epithelial lumen formation by mammary epithelial cells in 3-D Life Hydrogel:

MCF10A

Mammary epithelial cells (MCF10A) grown for 14 days in 3-D Life Dextran-PEG gel modified with RGD Peptide form epithelia enclosing a lumen (left panel). Lumen formation is impaired when a shRNA specific for the actin nucleator formin-like 2 (FMNL2) is expressed (right panel). Green: F-actin staining. Red: red fluorescent protein indicating activated shRNA transcription. For more information see Grikscheit K, Frank T, Wang Y, Grosse R. (2015). J. Cell Biol. 209:367-76. Figure courtesy of Dr. Katharina Grikscheit, University of Marburg, Germany.