|Hellwig, C. et al. (2018) Culture of human neurospheres in 3D scaffolds for developmental neurotoxicity testing. Toxicology in vitro 52:106-115 (Link)|
A novel peptide modification of 3-D Life Hydrogel was used to establish a neurosphere outgrowth assay for developmental neurotoxicity compound testing. The work shows how cell migration, differentiation to neurons and formation of neuronal networks is supported by the hydrogel.